YAF2 and RING1

Data Source:
BioGRID (two hybrid)

		YAF2	RING1
Description		YY1 associated factor 2	ring finger protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Ubiquitin Ligase Complex Sex Chromatin Nucleus Nucleoplasm Cytosol Nuclear Speck PcG Protein Complex PRC1 Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Chromatin Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity Ubiquitin-protein Transferase Activator Activity
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Anterior/posterior Pattern Specification Histone H2A Monoubiquitination Negative Regulation Of Transcription, DNA-templated Camera-type Eye Morphogenesis Regulation Of Catalytic Activity Negative Regulation Of G0 To G1 Transition
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6	Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Asthma ( 32296059) Wegener's granulomatosis ( 23740775)
Interacting Genes		29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42	34 interacting genes: APP BMI1 CBX4 CBX7 CBX8 E2F6 ELAC2 ERG FBXO38 FHL1 H3-4 NFKBID PCGF2 PCGF3 PCGF5 PCGF6 PHC1 PIK3R3 PTEN RB1 RNF2 RYBP TP53 TRIM55 TRIM63 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2E3 UBE2K YAF2 ZIM3
Entrez ID		10138	6015
HPRD ID		09606	03624
Ensembl ID		ENSG00000015153	ENSG00000204227
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	A0A1U9X8F2 Q06587
PDB IDs		2D9G
Enriched GO Terms of Interacting Partners?
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