DUSP23 and MKRN1

Data Source:
BioGRID (two hybrid)

		DUSP23	MKRN1
Description		dual specificity phosphatase 23	makorin ring finger protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Cellular_component Cytosol
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Protein Polyubiquitination Protein Ubiquitination
Pathways			AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs		4-Nitrophenyl Phosphate
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)	General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) ( 33208821) Immature fraction of reticulocytes ( 32888494) Number of sexual partners ( 30643258)
Interacting Genes		32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746	23 interacting genes: APC ASH2L BYSL CSNK1G1 DAXX DUSP23 EXOSC8 FADD FAM161A MAP1LC3B MTURN NAA10 OTUB2 RAD23A RAD23B SDCBP SLC13A1 UBASH3A UBE2D1 UBE2D3 UBE2D4 UBE2W YOD1
Entrez ID		54935	23608
HPRD ID		07908	09673
Ensembl ID		ENSG00000158716	ENSG00000133606
Uniprot IDs		A0A140VJI5 Q9BVJ7	Q9UHC7
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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