DUSP23 and TMOD3

Data Source:
BioGRID (two hybrid)

		DUSP23	TMOD3
Description		dual specificity phosphatase 23	tropomodulin 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Cytoskeleton Striated Muscle Thin Filament Adherens Junction Myofibril
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Actin Binding Tropomyosin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Muscle Contraction Actin Filament Organization Myofibril Assembly Erythrocyte Development Pointed-end Actin Filament Capping Cell-cell Adhesion Positive Regulation Of Mitotic Cell Cycle Phase Transition
Pathways			Striated Muscle Contraction
Drugs		4-Nitrophenyl Phosphate
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746	5 interacting genes: CDC42 CSNK2A1 DUSP23 MAP1LC3B TNFSF11
Entrez ID		54935	29766
HPRD ID		07908	10389
Ensembl ID		ENSG00000158716	ENSG00000138594
Uniprot IDs		A0A140VJI5 Q9BVJ7	Q9NYL9
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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