MKRN1 and CSNK1G1

Data Source:
BioGRID (two hybrid)

		MKRN1	CSNK1G1
Description		makorin ring finger protein 1	casein kinase 1 gamma 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination	Endocytosis Wnt Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs			2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) ( 33208821) Immature fraction of reticulocytes ( 32888494) Number of sexual partners ( 30643258)	Basophil count ( 32888494) General factor of neuroticism ( 30867560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monoclonal gammopathy of undetermined significance ( 30737484) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neuroticism ( 29255261) White blood cell count ( 32888494)
Interacting Genes		23 interacting genes: APC ASH2L BYSL CSNK1G1 DAXX DUSP23 EXOSC8 FADD FAM161A MAP1LC3B MTURN NAA10 OTUB2 RAD23A RAD23B SDCBP SLC13A1 UBASH3A UBE2D1 UBE2D3 UBE2D4 UBE2W YOD1	11 interacting genes: APP CEP76 FAM219A FOXO1 IKZF1 KRTAP10-7 MKRN1 PPP1R14A RELA RUNDC3B WDCP
Entrez ID		23608	53944
HPRD ID		09673	05886
Ensembl ID		ENSG00000133606	ENSG00000169118
Uniprot IDs		Q9UHC7	A0A024R5W3 Q8IXA3 Q9HCP0 U3KQB3
PDB IDs			2CMW
Enriched GO Terms of Interacting Partners?
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