COA6 and TTC19

Data Source:
BioGRID (two hybrid)

		COA6	TTC19
Description		cytochrome c oxidase assembly factor 6	tetratricopeptide repeat domain 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Intermembrane Space Plasma Membrane Respiratory Chain Complex IV	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome
	Molecular Function	RNA Binding Copper Ion Binding Protein Binding	Protein Binding
	Biological Process	Respiratory Chain Complex IV Assembly Plasma Membrane ATP Synthesis Coupled Electron Transport	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly
Pathways		Mitochondrial protein import
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		3 interacting genes: CABP2 DTX2 TTC19	44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688
Entrez ID		388753	54902
HPRD ID		18535	07899
Ensembl ID		ENSG00000168275	ENSG00000011295
Uniprot IDs		Q5JTJ3	A0A024RD83 Q6DKK2
PDB IDs		6NL3 6PCE 6PCF
Enriched GO Terms of Interacting Partners?
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