POU2AF1 and NAB1

Data Source:
BioGRID (two hybrid)

		POU2AF1	NAB1
Description		POU class 2 homeobox associating factor 1	NGFI-A binding protein 1
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GO Annotations	Cellular Component	RNA Polymerase II Transcription Regulator Complex	Nucleus
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding	Transcription Coregulator Activity Transcription Factor Binding
	Biological Process	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Endochondral Ossification Regulation Of Transcription, DNA-templated Schwann Cell Differentiation Myelination Regulation Of Epidermis Development Negative Regulation Of Transcription, DNA-templated
Pathways			NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Autoimmune traits (pleiotropy) ( 30572963) Bone mineral density (Ward's triangle area) ( 27397699) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Multiple sclerosis ( 31604244) Polymyositis ( 26362759) Primary biliary cholangitis ( 26394269) Pulse pressure ( 27841878) Rheumatoid arthritis ( 30572963) Systemic lupus erythematosus ( 33536424) Systemic sclerosis ( 31672989) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		54 interacting genes: CCDC120 DGCR6L FAM166B FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581	2 interacting genes: EGR1 POU2AF1
Entrez ID		5450	4664
HPRD ID		03126	02881
Ensembl ID		ENSG00000110777	ENSG00000138386
Uniprot IDs		Q16633	A8K8T1 B4DKG1 B8ZZS2 Q13506
PDB IDs		1CQT	2YUF
Enriched GO Terms of Interacting Partners?
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