POU2AF1 and FOXD2

Data Source:
BioGRID (two hybrid)

		POU2AF1	FOXD2
Description		POU class 2 homeobox associating factor 1	forkhead box D2
Image			No pdb structure
GO Annotations	Cellular Component	RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31152163) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Male-pattern baldness ( 29146897) Microalbuminuria ( 31511532) Obesity-related traits ( 23251661) Response to anti-depressant treatment in major depressive disorder ( 22041458) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532) Urinary albumin-to-creatinine ratio in diabetes ( 31511532)
Interacting Genes		54 interacting genes: CCDC120 DGCR6L FAM166B FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581	18 interacting genes: ARID5A CADPS CYSRT1 FOXH1 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 NOTO POU2AF1 TEX37 TLE5
Entrez ID		5450	2306
HPRD ID		03126	03735
Ensembl ID		ENSG00000110777	ENSG00000186564
Uniprot IDs		Q16633	O60548
PDB IDs		1CQT
Enriched GO Terms of Interacting Partners?
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