POU2AF1 and SUB1

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		POU2AF1	SUB1
Description		POU class 2 homeobox associating factor 1	SUB1 regulator of transcription
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GO Annotations	Cellular Component	RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Extracellular Exosome
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter SMAD Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Metabolite levels ( 23823483) PR interval ( 32439900)
Interacting Genes		54 interacting genes: CCDC120 DGCR6L FAM166B FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581	22 interacting genes: ADAP1 APP CBX5 CSNK2A1 CSTF2 EP300 GTF2A1L HNF4A HSF1 OTUD5 PCNA POLR2A POLR2B POU2AF1 PSIP1 RCOR1 REST SDCBP SP1 TAF1 TBP TP53
Entrez ID		5450	10923
HPRD ID		03126	02737
Ensembl ID		ENSG00000110777	ENSG00000113387
Uniprot IDs		Q16633	P53999 Q6IBA2
PDB IDs		1CQT	1PCF 2C62 2PHE 4USG 6YCS
Enriched GO Terms of Interacting Partners?
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