POU2AF1 and TFG

Data Source:
BioGRID (two hybrid)

		POU2AF1	TFG
Description		POU class 2 homeobox associating factor 1	trafficking from ER to golgi regulator
Image			No pdb structure
GO Annotations	Cellular Component	RNA Polymerase II Transcription Regulator Complex	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways			COPII-mediated vesicle transport
Drugs
Diseases			Non-small cell lung cancer Thyroid cancer
GWAS		Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Refractive error ( 32231278)
Interacting Genes		54 interacting genes: CCDC120 DGCR6L FAM166B FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581	73 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 C19orf54 CEP126 CEP55 CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PPP1R32 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SEC24A SF3A2 SF3B4 SMUG1 SPG21 STAT5B STH TBX19 TEX37 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34
Entrez ID		5450	10342
HPRD ID		03126	03932
Ensembl ID		ENSG00000110777	ENSG00000114354
Uniprot IDs		Q16633	Q05BK6 Q92734
PDB IDs		1CQT
Enriched GO Terms of Interacting Partners?
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