SERPINB5 and GSTO1

Data Source:
BioGRID (two hybrid)

		SERPINB5	GSTO1
Description		serpin family B member 5	glutathione S-transferase omega 1
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleoplasm Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity
	Biological Process	Morphogenesis Of An Epithelium Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion L-ascorbic Acid Metabolic Process Methylation Interleukin-12-mediated Signaling Pathway Xenobiotic Catabolic Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways			Methylation Glutathione conjugation Vitamin C (ascorbate) metabolism Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		S,S-(2-Hydroxyethyl)Thiocysteine	Glutathione
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)	Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF SMAD4 STK11 TBP TKT UCHL5 XRCC3	8 interacting genes: APP CEP126 EEF1G HSPB1 KAT5 RBM48 SERPINB5 SETDB1
Entrez ID		5268	9446
HPRD ID		01111	10401
Ensembl ID		ENSG00000206075	ENSG00000148834
Uniprot IDs		A0A024R2B6 P36952	P78417 V9HWG9
PDB IDs		1WZ9 1XQG 1XQJ 1XU8	1EEM 3LFL 3VLN 4IS0 4YQM 4YQU 4YQV 5UEH 5V3Q 5YVN 5YVO 6MHB 6MHC 6MHD 6PNM 6PNN 6PNO
Enriched GO Terms of Interacting Partners?
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