GSTO1 and CEP126

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GSTO1	CEP126
Description		glutathione S-transferase omega 1	centrosomal protein 126
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Cytoplasm Centrosome Midbody Ciliary Base
	Molecular Function	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity	Protein Binding
	Biological Process	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion L-ascorbic Acid Metabolic Process Methylation Interleukin-12-mediated Signaling Pathway Xenobiotic Catabolic Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly
Pathways		Methylation Glutathione conjugation Vitamin C (ascorbate) metabolism Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Glutathione
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: APP CEP126 EEF1G HSPB1 KAT5 RBM48 SERPINB5 SETDB1	87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZBED8 ZNF24
Entrez ID		9446	57562
HPRD ID		10401	17212
Ensembl ID		ENSG00000148834	ENSG00000110318
Uniprot IDs		P78417 V9HWG9	Q9P2H0
PDB IDs		1EEM 3LFL 3VLN 4IS0 4YQM 4YQU 4YQV 5UEH 5V3Q 5YVN 5YVO 6MHB 6MHC 6MHD 6PNM 6PNN 6PNO
Enriched GO Terms of Interacting Partners?
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