SERPINB5 and MDH1

Data Source:
BioGRID (two hybrid)

		SERPINB5	MDH1
Description		serpin family B member 5	malate dehydrogenase 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Extracellular Space Centrosome Cytosol Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Malic Enzyme Activity Protein Binding L-malate Dehydrogenase Activity Diiodophenylpyruvate Reductase Activity
	Biological Process	Morphogenesis Of An Epithelium Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis	Gluconeogenesis Tricarboxylic Acid Cycle Oxaloacetate Metabolic Process Malate Metabolic Process NADH Metabolic Process
Pathways			Gluconeogenesis
Drugs		S,S-(2-Hydroxyethyl)Thiocysteine	NADH Nicotinamide adenine dinucleotide phosphate Artenimol
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)	Asthma and attention deficit hyperactivity disorder ( 31619474) Blood protein levels ( 30072576) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF SMAD4 STK11 TBP TKT UCHL5 XRCC3	14 interacting genes: CDC42 CHRM2 EGFR ERBB2 FUS GPD1 HSD17B10 HSPB2 LTB4R2 MPP3 SERPINB5 TERF1 TERF2IP TP53
Entrez ID		5268	4190
HPRD ID		01111	01100
Ensembl ID		ENSG00000206075	ENSG00000014641
Uniprot IDs		A0A024R2B6 P36952	A0A5K1VW95 P40925 V9HWF2
PDB IDs		1WZ9 1XQG 1XQJ 1XU8
Enriched GO Terms of Interacting Partners?
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