SERPINB5 and BASP1

Data Source:
BioGRID (two hybrid)

		SERPINB5	BASP1
Description		serpin family B member 5	brain abundant membrane attached signal protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Chromatin Nucleus Cytoplasm Cytoskeleton Plasma Membrane COP9 Signalosome Nuclear Matrix PML Body Nuclear Speck Cell Junction Growth Cone Vesicle Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Morphogenesis Of An Epithelium Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis	Thorax And Anterior Abdomen Determination Gonad Development Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Mesenchymal To Epithelial Transition Positive Regulation Of Heart Growth Diaphragm Development Metanephric Mesenchyme Development Glomerular Visceral Epithelial Cell Differentiation Positive Regulation Of Metanephric Ureteric Bud Development
Pathways
Drugs		S,S-(2-Hydroxyethyl)Thiocysteine
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Melanoma ( 28212542) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)
Interacting Genes		26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF SMAD4 STK11 TBP TKT UCHL5 XRCC3	3 interacting genes: AGTR1 ATXN1 SERPINB5
Entrez ID		5268	10409
HPRD ID		01111	08389
Ensembl ID		ENSG00000206075	ENSG00000176788
Uniprot IDs		A0A024R2B6 P36952	P80723
PDB IDs		1WZ9 1XQG 1XQJ 1XU8
Enriched GO Terms of Interacting Partners?
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