RAB23 and ARFGAP1

Data Source:
BioGRID (two hybrid)

		RAB23	ARFGAP1
Description		RAB23, member RAS oncogene family	ADP ribosylation factor GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Endosome Membrane Endomembrane System Cell Junction Phagocytic Vesicle Membrane Phagocytic Vesicle	Golgi Membrane Cytosol Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Cellular Defense Response Negative Regulation Of Protein Import Into Nucleus GTP Metabolic Process Cilium Assembly Craniofacial Suture Morphogenesis	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity
Pathways		RAB geranylgeranylation	XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs
Diseases		Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS		Coronary artery disease ( 30104761) Systemic lupus erythematosus ( 28714469)
Interacting Genes		2 interacting genes: ARFGAP1 CREB3	34 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23
Entrez ID		51715	55738
HPRD ID		05850	06443
Ensembl ID		ENSG00000112210	ENSG00000101199
Uniprot IDs		A0A024RD41 Q9ULC3	Q53F62 Q8N6T3
PDB IDs			3DWD 3O47
Enriched GO Terms of Interacting Partners?
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