HSD17B14 and NUDT18

Data Source:
HPRD (two hybrid)

		HSD17B14	NUDT18
Description		hydroxysteroid 17-beta dehydrogenase 14	nudix hydrolase 18
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GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity
	Biological Process	Estrogen Biosynthetic Process Steroid Catabolic Process	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process
Pathways		Estrogen biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B	34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1
Entrez ID		51171	79873
HPRD ID		16801	07992
Ensembl ID		ENSG00000087076	ENSG00000275074
Uniprot IDs		A0A140VJH8 Q9BPX1	Q6ZVK8
PDB IDs		1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK	3GG6 4HVY
Enriched GO Terms of Interacting Partners?
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