HSD17B14 and PGLYRP3

Data Source:
BioGRID (two hybrid)

		HSD17B14	PGLYRP3
Description		hydroxysteroid 17-beta dehydrogenase 14	peptidoglycan recognition protein 3
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GO Annotations	Cellular Component	Cytosol	Extracellular Region Membrane Protein-containing Complex
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity	Protein Binding Zinc Ion Binding N-acetylmuramoyl-L-alanine Amidase Activity Peptidoglycan Immune Receptor Activity Peptidoglycan Binding Protein Heterodimerization Activity
	Biological Process	Estrogen Biosynthetic Process Steroid Catabolic Process	Peptidoglycan Catabolic Process Detection Of Bacterium Antimicrobial Humoral Response Killing Of Cells Of Other Organism Negative Regulation Of Interferon-gamma Production Negative Regulation Of Natural Killer Cell Differentiation Involved In Immune Response Innate Immune Response Defense Response To Gram-positive Bacterium Biological Process Involved In Interaction With Host Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Estrogen biosynthesis	Antimicrobial peptides
Drugs			2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE
Diseases
GWAS		Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)	Asthma ( 31619474)
Interacting Genes		24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B	4 interacting genes: CIDEB FAM209A HSD17B14 KRT34
Entrez ID		51171	114771
HPRD ID		16801	16297
Ensembl ID		ENSG00000087076	ENSG00000159527
Uniprot IDs		A0A140VJH8 Q9BPX1	Q96LB9
PDB IDs		1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK	1SK3 1SK4 1TWQ 2APH
Enriched GO Terms of Interacting Partners?
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