NUDT18 and APIP

Data Source:
HPRD (two hybrid)

		NUDT18	APIP
Description		nudix hydrolase 18	APAF1 interacting protein
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GO Annotations	Cellular Component	Cytosol	Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity
	Biological Process	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process	Apoptotic Process L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptosis Regulation Of ERK1 And ERK2 Cascade
Pathways			Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	19 interacting genes: APAF1 BAZ2B CFAP206 GORASP2 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 ZBTB25
Entrez ID		79873	51074
HPRD ID		07992	14725
Ensembl ID		ENSG00000275074	ENSG00000149089
Uniprot IDs		Q6ZVK8	Q96GX9
PDB IDs		3GG6 4HVY	4M6R
Enriched GO Terms of Interacting Partners?
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