HSD17B14 and MPG

Data Source:
BioGRID (two hybrid, two hybrid)

		HSD17B14	MPG
Description		hydroxysteroid 17-beta dehydrogenase 14	N-methylpurine DNA glycosylase
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GO Annotations	Cellular Component	Cytosol	Nucleoplasm Cytosol Mitochondrial Nucleoid
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity	Damaged DNA Binding Alkylbase DNA N-glycosylase Activity Protein Binding DNA-3-methyladenine Glycosylase Activity DNA N-glycosylase Activity DNA-7-methylguanine Glycosylase Activity DNA-7-methyladenine Glycosylase Activity DNA-3-methylguanine Glycosylase Activity
	Biological Process	Estrogen Biosynthetic Process Steroid Catabolic Process	Base-excision Repair DNA Dealkylation Involved In DNA Repair Depurination
Pathways		Estrogen biosynthesis	Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Displacement of DNA glycosylase by APEX1
Drugs			Cisplatin Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)	Blood protein levels ( 30072576) Glioblastoma ( 28346443) Hemoglobin levels ( 26366553) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)
Interacting Genes		24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B	13 interacting genes: APP CRK EP300 ESR1 FBXO7 GPR182 HSD17B14 MLH1 RAD23A RAD23B RXRA TERF2IP THRB
Entrez ID		51171	4350
HPRD ID		16801	06766
Ensembl ID		ENSG00000087076	ENSG00000103152
Uniprot IDs		A0A140VJH8 Q9BPX1	P29372 Q1W6H1
PDB IDs		1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK	1BNK 1EWN 1F4R 1F6O 3QI5 3UBY
Enriched GO Terms of Interacting Partners?
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