NUDT18 and PAICS

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUDT18	PAICS
Description		nudix hydrolase 18	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
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GO Annotations	Cellular Component	Cytosol	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding
	Biological Process	Nucleobase-containing Small Molecule Catabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Aspartic acid
Diseases
GWAS
Interacting Genes		34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1	18 interacting genes: CDC37 CEP76 CHD3 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 RAD54L2 RNF4 SMARCD1 TERF1 UBE2I ZMYM2
Entrez ID		79873	10606
HPRD ID		07992	01401
Ensembl ID		ENSG00000275074	ENSG00000128050
Uniprot IDs		Q6ZVK8	P22234
PDB IDs		3GG6 4HVY	2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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