TMX2 and PNLIPRP1

Data Source:
BioGRID (two hybrid)

		TMX2	PNLIPRP1
Description		thioredoxin related transmembrane protein 2	pancreatic lipase related protein 1
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane Membrane-bounded Organelle Mitochondria-associated Endoplasmic Reticulum Membrane	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Disulfide Oxidoreductase Activity Identical Protein Binding	Triglyceride Lipase Activity Calcium Ion Binding Protein Binding Lipase Activity
	Biological Process	Brain Development	Lipid Metabolic Process
Pathways			Digestion of dietary lipid
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Problematic alcohol use ( 32451486) Reticulocyte count ( 32888494) Schizophrenia ( 25056061 29483656)	Anger ( 24489884) Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369)
Interacting Genes		164 interacting genes: AGPAT3 AGPAT4 AGPAT5 AIG1 AQP6 ARV1 ASGR1 ASPH ATXN1 BDKRB1 BET1 BNIP1 BNIP2 BNIP3 BRICD5 BTN2A2 C2CD2L C3orf52 CCDC167 CCL2 CD81 CDIPT CDS2 CMTM7 COL8A2 COMMD8 COX20 CTSA CTXN3 CXCL16 CXorf66 CYBC1 CYP4F2 DERL1 DGAT2L6 EMD EMP3 F2RL1 FA2H FAM177A1 FAM241B FAM3C FAXDC2 FDFT1 FUNDC2 FXYD6-FXYD2 GIMAP1 GIMAP5 GJB2 HACD2 HHATL HMOX2 HSD17B11 HSD17B13 HSD3B7 HTATIP2 IER3 IER3IP1 IGFBP5 INSIG2 ITGAM LEPROT LEPROTL1 LHFPL5 LRAT MALL MFF MFSD14B MGLL MGST3 MIP MLN MS4A1 MTNR1A NAT8 NDUFA3 NINJ2 NRM NSDHL NSG1 ORMDL2 OTULINL PAEP PEDS1-UBE2V1 PEX16 PKMYT1 PLP2 PNLIPRP1 PRAF2 PRB1 PTAFR PTPN9 RABAC1 REEP2 REEP4 RFT1 RNF24 RTP2 RUSF1 SACM1L SCAMP5 SCD SELENOK SERF1A SERF1B SERP2 SFT2D1 SFXN1 SFXN3 SLC22A18 SLC22A2 SLC29A2 SLC35A1 SMAGP SMCO4 SMIM1 STATH STX12 STX3 STX7 THBD THSD7B TMBIM6 TMEM115 TMEM120A TMEM120B TMEM121 TMEM128 TMEM140 TMEM14B TMEM14C TMEM176A TMEM201 TMEM203 TMEM208 TMEM222 TMEM239 TMEM254 TMEM31 TMEM50B TMEM51 TMEM65 TMEM71 TMEM86B TMEM97 TPRG1 TRAM1L1 TREX1 TSNARE1 TSPAN2 TVP23B UBE2J1 UNC93A VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB WFDC2 YIF1A YIPF1 YIPF2 YIPF6	42 interacting genes: AQP2 BEST2 CD79A CERS4 CPLX4 CREB3 CYB5R3 EBP FAM209A FFAR2 GDAP1 GJA8 GJB5 GPR152 GPR42 GPX8 HSD17B13 KCNJ6 LEUTX LMNA LRRC25 MCFD2 MEOX2 MUC1 NDUFAF1 NEMP1 PEX12 RETREG3 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35C2 SLC39A2 SLC7A1 STX1A TMEM14B TMEM237 TMEM31 TMPPE TMX2 TSPAN8
Entrez ID		51075	5407
HPRD ID		07159	05109
Ensembl ID		ENSG00000213593	ENSG00000187021
Uniprot IDs		Q9Y320	P54315
PDB IDs		2DJ0	2PPL
Enriched GO Terms of Interacting Partners?
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