PNLIPRP1 and GJA8

Data Source:
BioGRID (two hybrid)

		PNLIPRP1	GJA8
Description		pancreatic lipase related protein 1	gap junction protein alpha 8
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Integral Component Of Plasma Membrane Connexin Complex
	Molecular Function	Triglyceride Lipase Activity Calcium Ion Binding Protein Binding Lipase Activity	Gap Junction Channel Activity Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process	Lens Development In Camera-type Eye Cell-cell Signaling Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways		Digestion of dietary lipid	Gap junction assembly
Drugs
Diseases
GWAS		Anger ( 24489884) Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369)	Retinopathy x type 2 diabetes interaction ( 32541925)
Interacting Genes		42 interacting genes: AQP2 BEST2 CD79A CERS4 CPLX4 CREB3 CYB5R3 EBP FAM209A FFAR2 GDAP1 GJA8 GJB5 GPR152 GPR42 GPX8 HSD17B13 KCNJ6 LEUTX LMNA LRRC25 MCFD2 MEOX2 MUC1 NDUFAF1 NEMP1 PEX12 RETREG3 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35C2 SLC39A2 SLC7A1 STX1A TMEM14B TMEM237 TMEM31 TMPPE TMX2 TSPAN8	121 interacting genes: ABL1 ACKR2 APOA2 APOD APOL3 AQP4 ARL6IP6 ATP6V0B C1GALT1 C2CD2L C3orf52 CCDC167 CCL4 CD53 CIAO2A CLDN19 CLDN4 CLEC1A CLN6 COX20 CTXN3 CXCL16 CYBC1 CYP4F2 DEFB121 DOLK ERMP1 FDFT1 FXYD6 GIMAP1 GIMAP5 GJB2 GPR108 GPR151 GPR61 GUCA2A IGFBP5 INSIG2 ITGAM KIR2DL3 LAPTM4B LAT LEPROTL1 LHFPL5 MAL MALL MARCHF2 MFSD11 MFSD6 MGST2 MIP MS4A13 ORMDL2 OTOP2 P2RY13 PGAP2 PLN PMP22 PNLIPRP1 PRAF2 PROKR2 PTPRN QRFPR REEP6 RNF152 RUSF1 RXFP4 S1PR5 SCARF1 SEC22B SEC22C SEC23A SFTPC SLC13A2 SLC13A5 SLC16A12 SLC16A13 SLC16A3 SLC30A3 SLC35A4 SLC35F1 SLC35F6 SLC38A4 SLC38A7 SLC39A2 SLC39A7 SLC39A9 SLC52A1 SLC66A1 SLC66A2 SLC8A3 SMCO4 SMIM1 STX1B STX8 THSD7B TJP1 TMBIM6 TMEM100 TMEM107 TMEM121 TMEM128 TMEM147 TMEM182 TMEM239 TMEM242 TMEM243 TMEM42 TMEM45A TMEM60 TMEM65 TMEM72 TMEM86B TSPAN33 TWSG1 UBXN8 UNC93A UPK1B VAMP5 YIF1A YIPF6
Entrez ID		5407	2703
HPRD ID		05109	02939
Ensembl ID		ENSG00000187021	ENSG00000121634
Uniprot IDs		P54315	P48165 X5D7G1
PDB IDs		2PPL
Enriched GO Terms of Interacting Partners?
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