CLDN11 and SPINT1

Data Source:
BioGRID (two hybrid)

		CLDN11	SPINT1
Description		claudin 11	serine peptidase inhibitor, Kunitz type 1
Image		No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Neurofilament Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Cell Junction Axon Basal Part Of Cell Tight Junction	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Cell Adhesion Spermatogenesis Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Tight Junction Assembly	Neural Tube Closure Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Positive Regulation Of Glial Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Cellular Response To BMP Stimulus Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		Tight junction interactions	MET Receptor Activation Signaling by MST1
Drugs
Diseases
GWAS		Blood glucose levels ( 31928498) Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction) ( 28820441) Prostate cancer ( 21743467)	Blood protein levels ( 30072576) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		12 interacting genes: AMIGO1 C16orf54 FNDC9 KLRC1 SHISA3 SMIM3 SPINT1 TMEM80 TNFSF14 TSPAN3 TSPAN4 ZP3	23 interacting genes: ADAM33 AGR3 CLDN11 CLEC7A FAM3C HGFAC HMGB1 KRTAP1-3 MAL NLGN3 SLC38A7 SMCO4 ST14 TENT5A TF TMEM109 TMEM190 TMEM97 TSPAN33 UBQLN2 UBQLN4 UPK1B VAMP5
Entrez ID		5010	6692
HPRD ID		03207	05494
Ensembl ID		ENSG00000013297	ENSG00000166145
Uniprot IDs		O75508	O43278
PDB IDs			1YC0 2MSX 4ISL 4ISN 4ISO 5EZD 5H7V
Enriched GO Terms of Interacting Partners?
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