MUTYH and BAAT

Data Source:
BioGRID (two hybrid)

		MUTYH	BAAT
Description		mutY DNA glycosylase	bile acid-CoA:amino acid N-acyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	Protein Binding Palmitoyl-CoA Hydrolase Activity N-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Choloyl-CoA Hydrolase Activity Acyl-CoA Hydrolase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Acyl-CoA Hydrolase Activity Long-chain Acyl-CoA Hydrolase Activity Very Long Chain Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	DNA Repair Base-excision Repair Mismatch Repair Depurination	Liver Development Bile Acid Conjugation Glycine Metabolic Process Protein Targeting To Peroxisome Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Taurine Metabolic Process Animal Organ Regeneration
Pathways			Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Peroxisomal protein import Peroxisomal protein import
Drugs			Glycine
Diseases		Familial adenomatous polyposis	Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS		Composite immunoglobulin trait (IgA/IgM) ( 28628107) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		19 interacting genes: AGTRAP APEX1 BAAT CYLC2 FANCC HRAS LMNA LRSAM1 MSANTD3 MSH6 PCNA RPA1 RPA4 SEC61B SIRT6 SMAD1 TDRD7 TSTD2 XPA	24 interacting genes: APC AURKA BCL10 BUB1 CDKN2A CTNNA1 DLC1 ERBB2 GOLGA8DP GOLGA8EP GOLGA8F MCC MLH1 MLH3 MUTYH ODC1 PDGFRL PEX5 PTPRJ RAD54B RB1 SLC7A11 SMAD4 SRC
Entrez ID		4595	570
HPRD ID		05380	08376
Ensembl ID		ENSG00000132781	ENSG00000136881
Uniprot IDs		D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7	Q14032
PDB IDs		1X51 3N5N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?