MUTYH and CYLC2

Data Source:
BioGRID (two hybrid)

		MUTYH	CYLC2
Description		mutY DNA glycosylase	cylicin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Nucleus Cytoskeletal Calyx
	Molecular Function	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	Structural Constituent Of Cytoskeleton
	Biological Process	DNA Repair Base-excision Repair Mismatch Repair Depurination	Cytoskeleton Organization Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases		Familial adenomatous polyposis
GWAS		Composite immunoglobulin trait (IgA/IgM) ( 28628107) Periventricular white matter hyperintensities ( 32517579)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		19 interacting genes: AGTRAP APEX1 BAAT CYLC2 FANCC HRAS LMNA LRSAM1 MSANTD3 MSH6 PCNA RPA1 RPA4 SEC61B SIRT6 SMAD1 TDRD7 TSTD2 XPA	13 interacting genes: AURKA BUB1 CDKN2A EGFR ERBB2 MAP2K4 MCC MLH1 MLH3 MUTYH NRAS SMAD2 STK11
Entrez ID		4595	1539
HPRD ID		05380	04945
Ensembl ID		ENSG00000132781	ENSG00000155833
Uniprot IDs		D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7	A0A024R146 Q14093 Q6PEJ5
PDB IDs		1X51 3N5N
Enriched GO Terms of Interacting Partners?
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