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BAAT and ODC1
Data Source:
BioGRID
(two hybrid)
BAAT
ODC1
Description
bile acid-CoA:amino acid N-acyltransferase
ornithine decarboxylase 1
Image
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Peroxisomal Matrix
Cytosol
Cellular_component
Cytoplasm
Cytosol
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Palmitoyl-CoA Hydrolase Activity
N-acyltransferase Activity
Transferase Activity, Transferring Acyl Groups
Choloyl-CoA Hydrolase Activity
Acyl-CoA Hydrolase Activity
Glycine N-choloyltransferase Activity
Carboxylic Ester Hydrolase Activity
Medium-chain Acyl-CoA Hydrolase Activity
Long-chain Acyl-CoA Hydrolase Activity
Very Long Chain Acyl-CoA Hydrolase Activity
Myristoyl-CoA Hydrolase Activity
Ornithine Decarboxylase Activity
Protein Binding
Protein Homodimerization Activity
Biological Process
Liver Development
Bile Acid Conjugation
Glycine Metabolic Process
Protein Targeting To Peroxisome
Fatty Acid Metabolic Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Bile Acid Metabolic Process
Taurine Metabolic Process
Animal Organ Regeneration
Regulation Of Cellular Amino Acid Metabolic Process
Polyamine Metabolic Process
Response To Virus
Putrescine Biosynthetic Process From Ornithine
Regulation Of Protein Catabolic Process
Pathways
Recycling of bile acids and salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Peroxisomal protein import
Peroxisomal protein import
Regulation of ornithine decarboxylase (ODC)
Metabolism of polyamines
Drugs
Glycine
Pyridoxal phosphate
Spermine
Putrescine
Pyridoxine phosphate
N-Pyridoxyl-Glycine-5-Monophosphate
L-Eflornithine
N(6)-(pyridoxal phosphate)-L-lysine
Geneticin
Eflornithine
Diseases
Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS
Interacting Genes
24 interacting genes:
APC
AURKA
BCL10
BUB1
CDKN2A
CTNNA1
DLC1
ERBB2
GOLGA8DP
GOLGA8EP
GOLGA8F
MCC
MLH1
MLH3
MUTYH
ODC1
PDGFRL
PEX5
PTPRJ
RAD54B
RB1
SLC7A11
SMAD4
SRC
18 interacting genes:
BAAT
CSNK2B
GORASP2
HEMGN
KAT5
MAP2K1
NANS
OAZ1
OAZ2
OAZ3
RSC1A1
SSR1
STX17
TDRD7
TK1
TMOD1
TSTD2
ZNF510
Entrez ID
570
4953
HPRD ID
08376
01324
Ensembl ID
ENSG00000136881
ENSG00000115758
Uniprot IDs
Q14032
B4DXF8
P11926
PDB IDs
1D7K
2ON3
2OO0
4ZGY
5BWA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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