MUTYH and TDRD7

Data Source:
BioGRID (two hybrid)

		MUTYH	TDRD7
Description		mutY DNA glycosylase	tudor domain containing 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Cytoplasm Mitochondrial Matrix Chromatoid Body Ribonucleoprotein Granule
	Molecular Function	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	MRNA Binding Protein Binding Protein N-terminus Binding
	Biological Process	DNA Repair Base-excision Repair Mismatch Repair Depurination	Lens Morphogenesis In Camera-type Eye Spermatogenesis Posttranscriptional Regulation Of Gene Expression Lens Fiber Cell Differentiation
Pathways
Drugs
Diseases		Familial adenomatous polyposis
GWAS		Composite immunoglobulin trait (IgA/IgM) ( 28628107) Periventricular white matter hyperintensities ( 32517579)	Bisphosphonate-associated atypical femoral fracture ( 31006051) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Interacting Genes		19 interacting genes: AGTRAP APEX1 BAAT CYLC2 FANCC HRAS LMNA LRSAM1 MSANTD3 MSH6 PCNA RPA1 RPA4 SEC61B SIRT6 SMAD1 TDRD7 TSTD2 XPA	20 interacting genes: ATXN2 BUB1 CABLES1 CCND1 CDK17 CDKN2A CTNNA1 DCC DLC1 FRAT1 GABPB1 MAGEA8 MLH1 MLH3 MSH2 MUTYH NRAS ODC1 STK11 TACC1
Entrez ID		4595	23424
HPRD ID		05380	11626
Ensembl ID		ENSG00000132781	ENSG00000196116
Uniprot IDs		D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7	Q8NHU6
PDB IDs		1X51 3N5N	3RCO
Enriched GO Terms of Interacting Partners?
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