BAAT and SLC7A11

Data Source:
HPRD (in vitro)

		BAAT	SLC7A11
Description		bile acid-CoA:amino acid N-acyltransferase	solute carrier family 7 member 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Rough Endoplasmic Reticulum Cytoskeleton Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Apical Part Of Cell Astrocyte Projection
	Molecular Function	Protein Binding Palmitoyl-CoA Hydrolase Activity N-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Choloyl-CoA Hydrolase Activity Acyl-CoA Hydrolase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Acyl-CoA Hydrolase Activity Long-chain Acyl-CoA Hydrolase Activity Very Long Chain Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity	Protein Binding L-amino Acid Transmembrane Transporter Activity Cystine:glutamate Antiporter Activity
	Biological Process	Liver Development Bile Acid Conjugation Glycine Metabolic Process Protein Targeting To Peroxisome Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Taurine Metabolic Process Animal Organ Regeneration	Amino Acid Transmembrane Transport Glutathione Metabolic Process Amino Acid Transport Visual Learning Response To Toxic Substance Response To Organic Cyclic Compound Ventricular System Development Striatum Development Adult Behavior Regulation Of Neutrophil Apoptotic Process Cellular Response To Oxidative Stress Glutathione Transmembrane Transport Response To Nicotine Regulation Of Cell Population Proliferation Regulation Of Melanin Biosynthetic Process Lung Alveolus Development Modulation Of Chemical Synaptic Transmission Regulation Of Synapse Organization Leukocyte Migration Regulation Of Protein Transport Response To Redox State Limb Development Lens Fiber Cell Differentiation Platelet Aggregation Glutamate Homeostasis L-glutamate Import Across Plasma Membrane Dipeptide Import Across Plasma Membrane Regulation Of Cysteine Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Glutathione Biosynthetic Process Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Glutamate Metabolic Process
Pathways		Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Peroxisomal protein import Peroxisomal protein import	Basigin interactions Amino acid transport across the plasma membrane
Drugs		Glycine	Cystine Glutamic acid Riluzole Sulfasalazine Acetylcysteine Thimerosal
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS			Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mood instability ( 31168069) Neurociticism ( 29500382)
Interacting Genes		24 interacting genes: APC AURKA BCL10 BUB1 CDKN2A CTNNA1 DLC1 ERBB2 GOLGA8DP GOLGA8EP GOLGA8F MCC MLH1 MLH3 MUTYH ODC1 PDGFRL PEX5 PTPRJ RAD54B RB1 SLC7A11 SMAD4 SRC	6 interacting genes: BAAT KRTAP1-1 KRTAP1-3 OTUB1 SLC3A2 TERT
Entrez ID		570	23657
HPRD ID		08376	09720
Ensembl ID		ENSG00000136881	ENSG00000151012
Uniprot IDs		Q14032	Q9UPY5
PDB IDs
Enriched GO Terms of Interacting Partners?
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