TDRD7 and MUTYH

Data Source:
BioGRID (two hybrid)

		TDRD7	MUTYH
Description		tudor domain containing 7	mutY DNA glycosylase
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GO Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Chromatoid Body Ribonucleoprotein Granule	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	MRNA Binding Protein Binding Protein N-terminus Binding	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Spermatogenesis Posttranscriptional Regulation Of Gene Expression Lens Fiber Cell Differentiation	DNA Repair Base-excision Repair Mismatch Repair Depurination
Pathways
Drugs
Diseases			Familial adenomatous polyposis
GWAS		Bisphosphonate-associated atypical femoral fracture ( 31006051) Refractive error ( 32231278) Waist-hip ratio ( 28552196)	Composite immunoglobulin trait (IgA/IgM) ( 28628107) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		20 interacting genes: ATXN2 BUB1 CABLES1 CCND1 CDK17 CDKN2A CTNNA1 DCC DLC1 FRAT1 GABPB1 MAGEA8 MLH1 MLH3 MSH2 MUTYH NRAS ODC1 STK11 TACC1	19 interacting genes: AGTRAP APEX1 BAAT CYLC2 FANCC HRAS LMNA LRSAM1 MSANTD3 MSH6 PCNA RPA1 RPA4 SEC61B SIRT6 SMAD1 TDRD7 TSTD2 XPA
Entrez ID		23424	4595
HPRD ID		11626	05380
Ensembl ID		ENSG00000196116	ENSG00000132781
Uniprot IDs		Q8NHU6	D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7
PDB IDs		3RCO	1X51 3N5N
Enriched GO Terms of Interacting Partners?
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