MBD1 and CHAF1A

Data Source:
HPRD (in vivo, two hybrid)

		MBD1	CHAF1A
Description		methyl-CpG binding domain protein 1	chromatin assembly factor 1 subunit A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Matrix Nuclear Speck	Chromatin Nucleus Protein-containing Complex CAF-1 Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding
	Biological Process	Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		25 interacting genes: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SP1 SUV39H1 TENM1 ZNF512B	47 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MEI4 MSH6 NOTO PABPC1 PAX6 PCBD2 PCNA POU6F2 RBFOX2 REL SERTAD1 SET SPOP STAT5B SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIB3 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408 ZNF620
Entrez ID		4152	10036
HPRD ID		01133	03148
Ensembl ID		ENSG00000141644	ENSG00000167670
Uniprot IDs		A8K654 B4DI41 B4DUR3 Q9UIS9	Q13111
PDB IDs		1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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