Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
L1CAM and MSN
Data Source:
HPRD
(in vivo)
L1CAM
MSN
Description
L1 cell adhesion molecule
moesin
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Focal Adhesion
Cell Surface
Integral Component Of Membrane
Axon
Dendrite
Neuronal Cell Body
Axonal Growth Cone
Collagen-containing Extracellular Matrix
Uropod
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Microvillus
Focal Adhesion
Cell Surface
Basolateral Plasma Membrane
Apical Plasma Membrane
Filopodium
Pseudopodium
Microvillus Membrane
Vesicle
Apical Part Of Cell
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Blood Microparticle
Molecular Function
Protein Binding
Axon Guidance Receptor Activity
Protein Domain Specific Binding
Double-stranded RNA Binding
Actin Binding
Signaling Receptor Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Enzyme Binding
Protein Kinase Binding
Cell Adhesion Molecule Binding
Biological Process
Chemotaxis
Cell Adhesion
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Cell-matrix Adhesion
Nervous System Development
Axon Guidance
Cell Migration
Neuron Projection Development
Positive Regulation Of Axon Extension
Synapse Organization
Leukocyte Migration
Axon Development
Immunological Synapse Formation
Cytoskeleton Organization
Leukocyte Cell-cell Adhesion
Regulation Of Cell Shape
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Viral Process
Gland Morphogenesis
Membrane To Membrane Docking
Interleukin-12-mediated Signaling Pathway
T Cell Proliferation
Establishment Of Epithelial Cell Apical/basal Polarity
Leukocyte Migration
Establishment Of Endothelial Barrier
T Cell Aggregation
Cellular Response To Testosterone Stimulus
Positive Regulation Of Podosome Assembly
T Cell Migration
Regulation Of Organelle Assembly
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Lymphocyte Migration
Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Basigin interactions
L1CAM interactions
L1CAM interactions
Recycling pathway of L1
Recycling pathway of L1
Interaction between L1 and Ankyrins
Interaction between L1 and Ankyrins
Signal transduction by L1
Recycling pathway of L1
Recycling pathway of L1
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Ethanol
Diseases
Hereditary spastic paraplegia (SPG)
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
L1 syndrome, including: ; X-linked hydrocephalus; MASA syndrome; X-linked complicated spastic paraplegia type I ; X-linked partial agenesis of corpus callosum
GWAS
Male-pattern baldness (
28196072
)
Interacting Genes
24 interacting genes:
ANK1
ANK2
CNTN1
CNTN2
CSNK2A1
EZR
FGFR1
ITGA5
ITGAV
LINC00839
MSN
NCAM1
NCAN
NRP1
NRP2
NUMB
PEA15
PLXNA1
PLXNB1
PRNP
RANBP9
RDX
RPS6KA1
RPS6KA2
31 interacting genes:
BCAP31
CD44
CD46
CD93
CDK11B
ERBB2
EZR
ICAM1
ICAM2
ICAM3
L1CAM
LINC01554
LMO2
MYBPC2
NCF1
NCF4
PLEC
PPM1A
PPM1B
PRKCQ
ROCK1
SELL
SELPLG
SLC9A3R1
SMURF1
SPN
TERF1
TRIM15
TSC1
VCAM1
VPS11
Entrez ID
3897
4478
HPRD ID
02394
02399
Ensembl ID
ENSG00000198910
ENSG00000147065
Uniprot IDs
P32004
P26038
V9HWC0
PDB IDs
1E5W
1EF1
1SGH
6TXQ
6TXS
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?