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TRIM23 and CDC73
Data Source:
BioGRID
(two hybrid)
TRIM23
CDC73
Description
tripartite motif containing 23
cell division cycle 73
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Cytoplasm
Lysosomal Membrane
Plasma Membrane
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytosol
Cdc73/Paf1 Complex
Molecular Function
GTPase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
GTP Binding
Enzyme Activator Activity
Zinc Ion Binding
GDP Binding
Identical Protein Binding
RNA Polymerase II Complex Binding
Protein Binding
Biological Process
Intracellular Protein Transport
Viral Process
Vesicle-mediated Transport
Protein Ubiquitination
Innate Immune Response
Regulation Of Catalytic Activity
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Endodermal Cell Fate Commitment
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
MRNA Polyadenylation
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Histone Monoubiquitination
Wnt Signaling Pathway
Protein Ubiquitination
Stem Cell Population Maintenance
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of MRNA 3'-end Processing
Protein Destabilization
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Histone H2B Ubiquitination
Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex
Negative Regulation Of Apoptotic Process
Negative Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Fibroblast Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Cellular Response To Lipopolysaccharide
Positive Regulation Of Cell Cycle G1/S Phase Transition
Beta-catenin-TCF Complex Assembly
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Formation of RNA Pol II elongation complex
Formation of the beta-catenin:TCF transactivating complex
Hedgehog 'on' state
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
GWAS
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Chronotype (
30696823
)
Ovarian disease with few adhesions (
28333195
)
Photic sneeze reflex (
27182965
)
Subcutaneous adipose tissue (
22589738
)
Takayasu arteritis (
25604533
)
White matter hyperintensity burden (
25663218
)
Interacting Genes
218 interacting genes:
ACTN4
AKTIP
ANKRD36BP1
ANKRD55
AP3M1
AQP1
ARFGAP1
ARHGEF3
ARNT2
ATPAF2
ATXN7
BAG1
BAZ2B
BICRAL
BRME1
C2CD6
C8orf33
CARD9
CBX8
CCDC13
CCDC146
CCDC25
CCDC33
CDC20B
CDC73
CDR2
CFAP53
CHP1P2
COX5B
CPNE7
CREB5
CSRP2
CWF19L2
CXCL14
CYTH1
CYTH2
DCX
DEPP1
DMC1
DMRT3
DNAAF4
DOCK2
EAF2
EHHADH
EIF3D
ENKD1
EPN2
EXOC3-AS1
FAM110A
FAM133A
FAM193B
FAM83A
FAM90A1
FBF1
FHIT
FLAD1
FXR2
GAD1
GATA2
GCC2-AS1
GEM
GGA2
GGA3
GLIDR
GMCL2
GPANK1
GPKOW
HAPLN2
HAUS1
HGS
HNRNPLL
HOXB5
HSPB7
IL16
IQCE
IQUB
JOSD1
JRK
KAT5
KIFC3
KLHL42
KRT6A
KRT75
KRT76
LAGE3
LENG1
LGALS14
LGALS3
LGALS8
LINC00526
LINC01018
LMO2
LMO3
LNX1
MDM2
MKRN3
MLH1
MORN4
MRPL4
MRPL45
MSRB3
MTFR2
MYEF2
MYOM1
MYOZ1
NAB2
NEDD9
NEK6
NFU1
NOXA1
NTAQ1
NUDT21
NXT2
PDE4D
PHF1
PIAS2
PIK3R2
PITX1
PKP4
PLEKHA2
POLI
POLL
POM121
PPIL2
PPP1R15B
PPP1R18
PRPF18
PRPF31
PSMA1
PSMB1
RAD18
RAMAC
RCAN3
RIBC1
RIBC2
RIN1
RNF126
RNF213
RNF32
RNF34
RNF6
RSRC2
RTP5
RUFY1
SCNM1
SF1
SH2D4A
SIAH1
SIRPA
SLC25A6
SMG9
SNAI1
SNAI2
SNRPB
SNRPB2
SNW1
SORBS3
SPG21
STK19
SUMO1P1
TACO1
TASOR2
TBC1D22B
TCEA2
TCEANC
TEPSIN
TEX33
TMSB4X
TNFAIP3
TRAF1
TRAIP
TRIM27
TRIM29
TRIM31
TRIM32
TRIM42
TRIM55
TRIM63
TROAP
TSEN54
TSG101
TSHZ3
TXNDC5
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2H
UBE2I
UBE2L3
UBE2N
UBE2U
UBE2W
UBOX5
UBQLN1
USP2
USP20
USP21
UTP23
VGLL1
WDR25
ZBTB16
ZBTB4
ZC2HC1C
ZFAND2A
ZNF20
ZNF250
ZNF408
ZNF417
ZNF474
ZNF564
ZNF581
ZNF587
ZNF688
ZNF835
35 interacting genes:
ALAS1
ANXA6
CEP70
CTNNB1
DDAH2
FAF1
FSD2
GC
GOLGA2
GOLGA6L9
H1-2
HAP1
HSF2BP
HSPA4
ITFG1
KASH5
KCNH2
KIAA1549
KIDINS220
MCM3AP
MTUS2
MYC
PICK1
PITHD1
RABEP1
RNF20
RNF40
TCEA1
TCF4
TFCP2
TOMM20
TRIM23
TSGA10
VPS37B
WWC1
Entrez ID
373
79577
HPRD ID
03449
09581
Ensembl ID
ENSG00000113595
ENSG00000134371
Uniprot IDs
P36406
Q6P1J9
PDB IDs
5VZV
5VZW
5YDE
5YDF
6TED
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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