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TRIM23 and AQP1
Data Source:
BioGRID
(two hybrid)
TRIM23
AQP1
Description
tripartite motif containing 23
aquaporin 1 (Colton blood group)
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Cytoplasm
Lysosomal Membrane
Plasma Membrane
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Molecular Function
GTPase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
GTP Binding
Enzyme Activator Activity
Zinc Ion Binding
GDP Binding
Identical Protein Binding
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Biological Process
Intracellular Protein Transport
Viral Process
Vesicle-mediated Transport
Protein Ubiquitination
Innate Immune Response
Regulation Of Catalytic Activity
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Defense Response To Gram-negative Bacterium
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Acetazolamide
B-nonylglucoside
Mersalyl
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Interacting Genes
218 interacting genes:
ACTN4
AKTIP
ANKRD36BP1
ANKRD55
AP3M1
AQP1
ARFGAP1
ARHGEF3
ARNT2
ATPAF2
ATXN7
BAG1
BAZ2B
BICRAL
BRME1
C2CD6
C8orf33
CARD9
CBX8
CCDC13
CCDC146
CCDC25
CCDC33
CDC20B
CDC73
CDR2
CFAP53
CHP1P2
COX5B
CPNE7
CREB5
CSRP2
CWF19L2
CXCL14
CYTH1
CYTH2
DCX
DEPP1
DMC1
DMRT3
DNAAF4
DOCK2
EAF2
EHHADH
EIF3D
ENKD1
EPN2
EXOC3-AS1
FAM110A
FAM133A
FAM193B
FAM83A
FAM90A1
FBF1
FHIT
FLAD1
FXR2
GAD1
GATA2
GCC2-AS1
GEM
GGA2
GGA3
GLIDR
GMCL2
GPANK1
GPKOW
HAPLN2
HAUS1
HGS
HNRNPLL
HOXB5
HSPB7
IL16
IQCE
IQUB
JOSD1
JRK
KAT5
KIFC3
KLHL42
KRT6A
KRT75
KRT76
LAGE3
LENG1
LGALS14
LGALS3
LGALS8
LINC00526
LINC01018
LMO2
LMO3
LNX1
MDM2
MKRN3
MLH1
MORN4
MRPL4
MRPL45
MSRB3
MTFR2
MYEF2
MYOM1
MYOZ1
NAB2
NEDD9
NEK6
NFU1
NOXA1
NTAQ1
NUDT21
NXT2
PDE4D
PHF1
PIAS2
PIK3R2
PITX1
PKP4
PLEKHA2
POLI
POLL
POM121
PPIL2
PPP1R15B
PPP1R18
PRPF18
PRPF31
PSMA1
PSMB1
RAD18
RAMAC
RCAN3
RIBC1
RIBC2
RIN1
RNF126
RNF213
RNF32
RNF34
RNF6
RSRC2
RTP5
RUFY1
SCNM1
SF1
SH2D4A
SIAH1
SIRPA
SLC25A6
SMG9
SNAI1
SNAI2
SNRPB
SNRPB2
SNW1
SORBS3
SPG21
STK19
SUMO1P1
TACO1
TASOR2
TBC1D22B
TCEA2
TCEANC
TEPSIN
TEX33
TMSB4X
TNFAIP3
TRAF1
TRAIP
TRIM27
TRIM29
TRIM31
TRIM32
TRIM42
TRIM55
TRIM63
TROAP
TSEN54
TSG101
TSHZ3
TXNDC5
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2H
UBE2I
UBE2L3
UBE2N
UBE2U
UBE2W
UBOX5
UBQLN1
USP2
USP20
USP21
UTP23
VGLL1
WDR25
ZBTB16
ZBTB4
ZC2HC1C
ZFAND2A
ZNF20
ZNF250
ZNF408
ZNF417
ZNF474
ZNF564
ZNF581
ZNF587
ZNF688
ZNF835
134 interacting genes:
ADAMTSL4
AMOT
AQP6
BCL2L13
BEGAIN
BHLHB9
BLZF1
BMF
CCDC136
CCDC57
CCDC85B
CCNDBP1
CD79A
CDR2
CEP44
CLDN5
COMP
CPLX4
CREB3
CRTAC1
CSRNP1
CYSRT1
EFEMP2
EPHB2
ESM1
EVI2B
FAM161A
FAM209A
FNDC9
FOS
FSD2
GET1
GJB5
GLI1
GOLGA2
GPR37L1
GPX8
IFT20
IGFBP6
IHO1
IKZF2
IKZF3
IL21R
KCNK5
KCTD17
KCTD9
KHDRBS3
KIAA1958
KLHL26
KRT31
KRT33B
KRT37
KRT40
KRTAP1-1
KRTAP1-5
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-4
KRTAP3-2
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE1A
LDLRAD1
LDOC1
LIME1
LMNA
LPXN
LRRC59
MDFI
MGST3
MID2
MIF4GD
MKRN3
MRM1
MTUS2
MUC1
MYF5
NBPF19
NBPF22P
NBPF6
NOTCH2NLA
NUTM1
PGPEP1
PICK1
PLA2G10
PLSCR2
PPARA
PRDM14
PRDM6
RBAK
REL
RGS17
RGS20
RIMBP3
RNF122
SAR1A
SIAH1
SIVA1
SLC15A2
SLC39A2
SPDYA
SPRED1
SPRED2
SPRY2
SPRY3
SPRYD7
SSMEM1
TCF4
TMEM237
TMEM38B
TMEM45B
TMEM80
TMPRSS2
TNK2
TNS2
TRAF1
TRAF2
TRIM23
TRIM37
TRIM41
TRIM42
TRIM7
TRIP6
TSC1
ZBTB39
ZIM2
ZNF16
ZNF398
ZNF792
Entrez ID
373
358
HPRD ID
03449
00140
Ensembl ID
ENSG00000113595
ENSG00000240583
Uniprot IDs
P36406
A0A024RA31
P29972
PDB IDs
5VZV
5VZW
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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