PPM1J and GPR37

Data Source:
BioGRID (two hybrid)

		PPM1J	GPR37
Description		protein phosphatase, Mg2+/Mn2+ dependent 1J	G protein-coupled receptor 37
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex
	Molecular Function	Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Protein Dephosphorylation	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 31152163) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 32341527 26237428) Nevus count or cutaneous melanoma ( 32341527) Reading and spelling ( 23738518) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: ADORA2A CSN1S1 F2RL1 GPR37 LGALS14 PLEKHN1 PTAFR SMARCD1 SPG21 SUMO1 UBE2I	51 interacting genes: ADGRB1 ADORA2A ADRA1A ADRB2 BNIP3 CCNQ CNTN1 DRD2 ERGIC3 FA2H FKBP8 FUCA2 G6PC3 GABARAPL2 GABBR1 GHITM GLP1R GPR17 GRIP1 HDGF HLA-C HSP90B1 HSPA1A HTR2C HTR4 IFITM3 JKAMP LTB4R2 P4HTM PPM1J PRKN SDCBP SLC37A1 SLC3A2 SLC41A3 SLC8A2 SPATA2L STUB1 SYVN1 TAFA5 TMED1 TMEM161A TMEM175 TMEM231 TMEM63A TTYH1 TTYH2 WLS YIF1A YIF1B ZDHHC11
Entrez ID		333926	2861
HPRD ID		15171	03992
Ensembl ID		ENSG00000155367	ENSG00000170775
Uniprot IDs		Q5JR12	O15354
PDB IDs
Enriched GO Terms of Interacting Partners?
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