HSPA9 and SUPT6H

Data Source:
BioGRID (pull down)

		HSPA9	SUPT6H
Description		heat shock protein family A (Hsp70) member 9	SPT6 homolog, histone chaperone and transcription elongation factor
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GO Annotations	Cellular Component	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome MIB Complex	Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding	DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	Protein Export From Nucleus Inner Mitochondrial Membrane Organization Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Hemopoiesis	Blastocyst Formation Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Chromatin Maintenance
Pathways		Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)	Pulse pressure ( 30578418)
Interacting Genes		26 interacting genes: APP DNAJC19 DNLZ ERBB2 ERCC6 FGF1 HSP90B1 HSPBP1 LAMTOR5 LINC01554 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG	13 interacting genes: AKT1 CSNK2A1 DNAJB6 EGFR ERBB2 ERCC6 GAB1 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2
Entrez ID		3313	6830
HPRD ID		02770	03211
Ensembl ID		ENSG00000113013	ENSG00000109111
Uniprot IDs		A0A384P5G6 P38646	Q7KZ85
PDB IDs		3N8E 4KBO 6NHK 6P2U 6PMT	6GME 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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