HSPA9 and DNAJC19

Data Source:
BioGRID (enzymatic study, enzymatic study)

		HSPA9	DNAJC19
Description		heat shock protein family A (Hsp70) member 9	DnaJ heat shock protein family (Hsp40) member C19
Image			No pdb structure
GO Annotations	Cellular Component	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome MIB Complex	PAM Complex, Tim23 Associated Import Motor Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Protein-containing Complex Inner Mitochondrial Membrane Protein Complex Matrix Side Of Mitochondrial Inner Membrane
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding	ATPase Activator Activity Protein Binding
	Biological Process	Protein Export From Nucleus Inner Mitochondrial Membrane Organization Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Hemopoiesis	Protein Folding Protein Targeting To Mitochondrion Visual Perception Protein Import Into Mitochondrial Matrix Positive Regulation Of ATPase Activity Genitalia Development Regulation Of Cardiolipin Metabolic Process
Pathways		Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Mitochondrial protein import
Drugs
Diseases			3-Methylglutaconic aciduria (MGCA)
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)	Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		26 interacting genes: APP DNAJC19 DNLZ ERBB2 ERCC6 FGF1 HSP90B1 HSPBP1 LAMTOR5 LINC01554 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG	4 interacting genes: APP HSPA9 MCPH1 PAM16
Entrez ID		3313	131118
HPRD ID		02770	12349
Ensembl ID		ENSG00000113013	ENSG00000205981
Uniprot IDs		A0A384P5G6 P38646	A0A0S2Z5X1 Q96DA6
PDB IDs		3N8E 4KBO 6NHK 6P2U 6PMT
Enriched GO Terms of Interacting Partners?
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