HSPA9 and TIMM44

Data Source:
BioGRID (pull down)

		HSPA9	TIMM44
Description		heat shock protein family A (Hsp70) member 9	translocase of inner mitochondrial membrane 44
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GO Annotations	Cellular Component	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome MIB Complex	Fibrillar Center Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding	Protein Binding ATP Binding Chaperone Binding
	Biological Process	Protein Export From Nucleus Inner Mitochondrial Membrane Organization Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Hemopoiesis	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix
Pathways		Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Mitochondrial protein import
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		26 interacting genes: APP DNAJC19 DNLZ ERBB2 ERCC6 FGF1 HSP90B1 HSPBP1 LAMTOR5 LINC01554 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG	8 interacting genes: ARAF CCDC57 CMTM5 HSPA9 PRPF6 SFT2D2 TIMM17A UBASH3A
Entrez ID		3313	10469
HPRD ID		02770	05450
Ensembl ID		ENSG00000113013	ENSG00000104980
Uniprot IDs		A0A384P5G6 P38646	O43615
PDB IDs		3N8E 4KBO 6NHK 6P2U 6PMT	2CW9
Enriched GO Terms of Interacting Partners?
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