HSPA9 and NELFB

Data Source:
BioGRID (pull down)

		HSPA9	NELFB
Description		heat shock protein family A (Hsp70) member 9	negative elongation factor complex member B
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GO Annotations	Cellular Component	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome MIB Complex	Nucleoplasm Cytoplasm NELF Complex
	Molecular Function	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding	RNA Binding Protein Binding
	Biological Process	Protein Export From Nucleus Inner Mitochondrial Membrane Organization Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Hemopoiesis	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Cell Population Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Viral Transcription Negative Regulation Of Stem Cell Differentiation
Pathways		Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		26 interacting genes: APP DNAJC19 DNLZ ERBB2 ERCC6 FGF1 HSP90B1 HSPBP1 LAMTOR5 LINC01554 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG	16 interacting genes: BRCA1 CEBPE DENR ESR1 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFCD NELFE NTRK3 RAD51 TPRX1
Entrez ID		3313	25920
HPRD ID		02770	10845
Ensembl ID		ENSG00000113013	ENSG00000188986
Uniprot IDs		A0A384P5G6 P38646	Q8WX92
PDB IDs		3N8E 4KBO 6NHK 6P2U 6PMT	6GML
Enriched GO Terms of Interacting Partners?
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