HMGN1 and KLF13

Data Source:
HPRD (in vivo)

		HMGN1	KLF13
Description		high mobility group nucleosome binding domain 1	Kruppel like factor 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Chromatin Nucleus
	Molecular Function	DNA Binding Chromatin Binding Nucleosomal DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription-coupled Nucleotide-excision Repair Chromatin Organization Positive Regulation Of DNA-templated Transcription, Elongation	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases
GWAS		LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)	Brain volume in infants (intracranial brain volume) ( 28763065) Deep white matter hyperintensities ( 32517579) Eosinophilic esophagitis ( 25017104) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494) Psoriasis ( 28537254) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		21 interacting genes: CDC42 CHEK2 EP300 HMGN2 HPF1 IRF2 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 YWHAZ	9 interacting genes: CREBBP EP300 KAT2B PCBD1 PRPF4B SERPINH1 SIN3A SREBF1 SREBF2
Entrez ID		3150	51621
HPRD ID		01231	05620
Ensembl ID		ENSG00000205581	ENSG00000169926
Uniprot IDs		P05114 Q6NSG7	Q9Y2Y9 X5DNR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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