HMGN1 and SLC38A3

Data Source:
BioGRID (two hybrid)

		HMGN1	SLC38A3
Description		high mobility group nucleosome binding domain 1	solute carrier family 38 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	DNA Binding Chromatin Binding Nucleosomal DNA Binding	L-histidine Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Antiporter Activity
	Biological Process	Transcription-coupled Nucleotide-excision Repair Chromatin Organization Positive Regulation Of DNA-templated Transcription, Elongation	Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport Brain Development Female Pregnancy L-alanine Transport Histidine Transport Cellular Response To Potassium Ion Starvation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Acidic PH L-histidine Transmembrane Transport Transport Across Blood-brain Barrier Positive Regulation Of Glutamine Transport
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER	Amino acid transport across the plasma membrane
Drugs			Histidine Asparagine
Diseases
GWAS		LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)	Body mass index ( 26426971) Conotruncal heart defects (maternal effects) ( 28468790) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sleep duration (short sleep) ( 30846698) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		21 interacting genes: CDC42 CHEK2 EP300 HMGN2 HPF1 IRF2 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 YWHAZ	3 interacting genes: COL6A2 HMGN1 SETDB1
Entrez ID		3150	10991
HPRD ID		01231	11980
Ensembl ID		ENSG00000205581	ENSG00000188338
Uniprot IDs		P05114 Q6NSG7	Q99624
PDB IDs
Enriched GO Terms of Interacting Partners?
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