HMGN1 and ETS2

Data Source:
BioGRID (biochemical)

		HMGN1	ETS2
Description		high mobility group nucleosome binding domain 1	ETS proto-oncogene 2, transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	DNA Binding Chromatin Binding Nucleosomal DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription-coupled Nucleotide-excision Repair Chromatin Organization Positive Regulation Of DNA-templated Transcription, Elongation	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER	Oncogene Induced Senescence
Drugs
Diseases
GWAS		LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)	Adult body size ( 32376654) Body mass index ( 25673413) Body size at age 10 ( 32376654) C-reactive protein levels ( 30388399) Central corneal thickness ( 32528159) Eye morphology ( 29921221) Fibrinogen levels ( 28107422) Fractures ( 30158200) Intraocular pressure ( 29617998) Non-small cell lung cancer (survival) ( 21079520) Periodontitis (Mean PAL) ( 24024966) Schizophrenia ( 30285260) TPE interval (response to exercise) ( 32386560)
Interacting Genes		21 interacting genes: CDC42 CHEK2 EP300 HMGN2 HPF1 IRF2 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 YWHAZ	20 interacting genes: CDK10 COP1 CREBBP EP300 ERG ETS1 FOS GATA3 JUN NCOR1 NR3C1 POU5F1 SMARCA4 SPI1 SRA1 SRC STAT5B TDP2 ZFYVE9 ZMYND11
Entrez ID		3150	2114
HPRD ID		01231	01263
Ensembl ID		ENSG00000205581	ENSG00000157557
Uniprot IDs		P05114 Q6NSG7	P15036
PDB IDs			4BQA 4MHV
Enriched GO Terms of Interacting Partners?
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