ETS2 and ZMYND11

Data Source:
HPRD (in vivo, two hybrid)

		ETS2	ZMYND11
Description		ETS proto-oncogene 2, transcription factor	zinc finger MYND-type containing 11
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane	Nucleus Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Sequence-specific Double-stranded DNA Binding	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Chromatin Organization Cell Cycle Viral Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Oncogene Induced Senescence
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 25673413) Body size at age 10 ( 32376654) C-reactive protein levels ( 30388399) Central corneal thickness ( 32528159) Eye morphology ( 29921221) Fibrinogen levels ( 28107422) Fractures ( 30158200) Intraocular pressure ( 29617998) Non-small cell lung cancer (survival) ( 21079520) Periodontitis (Mean PAL) ( 24024966) Schizophrenia ( 30285260) TPE interval (response to exercise) ( 32386560)	Malaria ( 31844061)
Interacting Genes		20 interacting genes: CDK10 COP1 CREBBP EP300 ERG ETS1 FOS GATA3 JUN NCOR1 NR3C1 POU5F1 SMARCA4 SPI1 SRA1 SRC STAT5B TDP2 ZFYVE9 ZMYND11	24 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1
Entrez ID		2114	10771
HPRD ID		01263	09830
Ensembl ID		ENSG00000157557	ENSG00000015171
Uniprot IDs		P15036	B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2
PDB IDs		4BQA 4MHV	4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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