GPS1 and TBC1D17

Data Source:
HPRD (two hybrid)

		GPS1	TBC1D17
Description		G protein pathway suppressor 1	TBC1 domain family member 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Autophagosome Cytosol Recycling Endosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification	Intracellular Protein Transport Autophagy Retrograde Transport, Endosome To Golgi Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	TBC/RABGAPs
Drugs
Diseases
GWAS
Interacting Genes		29 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 ELOB IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL	19 interacting genes: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1
Entrez ID		2873	79735
HPRD ID		15991	15471
Ensembl ID		ENSG00000169727	ENSG00000104946
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	Q9HA65
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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