GPS1 and SAP130

		GPS1	SAP130
Description		G protein pathway suppressor 1	Sin3A associated protein 130
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Nuclear Speck Sin3-type Complex
	Molecular Function	GTPase Inhibitor Activity Protein Binding
	Biological Process	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	HATs acetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS			Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		29 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 ELOB IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL	6 interacting genes: ARID4B CCR9 CUL2 GPS1 MYC SMAD3
Entrez ID		2873	79595
HPRD ID		15991	18015
Ensembl ID		ENSG00000169727	ENSG00000136715
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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