GPS1 and COPS4

Data Source:
BioGRID (pull down)

		GPS1	COPS4
Description		G protein pathway suppressor 1	COP9 signalosome subunit 4
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GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome	Nucleus Nucleoplasm Cytosol Synaptic Vesicle COP9 Signalosome Nuclear Speck Cell Junction
	Molecular Function	GTPase Inhibitor Activity Protein Binding	Protein Binding NEDD8-specific Protease Activity
	Biological Process	Inactivation Of MAPK Activity Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair JNK Cascade Negative Regulation Of GTPase Activity Post-translational Protein Modification	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition Transcription-coupled Nucleotide-excision Repair Post-translational Protein Modification
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: CNOT2 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 ELOB IP6K1 ITPK1 RBX1 SAP130 SENP8 SKP1 SKP2 TBC1D17 TP53 TRIM55 TRIM63 VHL	24 interacting genes: BRME1 CCDC85B COPS2 COPS3 COPS5 COPS6 COPS7A COPS7B COPS8 CUL5 FOS GPS1 IKBKB IL1RN KRT19 MBIP PCDHB12 PEX14 RBX1 RCBTB2 TP53 UBQLN1 USHBP1 YWHAQ
Entrez ID		2873	51138
HPRD ID		15991	09888
Ensembl ID		ENSG00000169727	ENSG00000138663
Uniprot IDs		A0A096LP07 A0A096LPJ3 C9JFE4 Q13098	A0A0S2Z5H7 B3KM48 D6RAX7 Q9BT78
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N	4D0P 4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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