SLC3A2 and SLC7A11

Data Source:
HPRD (in vivo)

		SLC3A2	SLC7A11
Description		solute carrier family 3 member 2	solute carrier family 7 member 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cell Junction Melanosome Extracellular Exosome Amino Acid Transport Complex	Rough Endoplasmic Reticulum Cytoskeleton Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Apical Part Of Cell Astrocyte Projection
	Molecular Function	RNA Binding Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Cadherin Binding	Protein Binding L-amino Acid Transmembrane Transporter Activity Cystine:glutamate Antiporter Activity
	Biological Process	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Phenylalanine Transport Tryptophan Transport Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Leukocyte Migration Leucine Import Across Plasma Membrane L-alpha-amino Acid Transmembrane Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane	Amino Acid Transmembrane Transport Glutathione Metabolic Process Amino Acid Transport Visual Learning Response To Toxic Substance Response To Organic Cyclic Compound Ventricular System Development Striatum Development Adult Behavior Regulation Of Neutrophil Apoptotic Process Cellular Response To Oxidative Stress Glutathione Transmembrane Transport Response To Nicotine Regulation Of Cell Population Proliferation Regulation Of Melanin Biosynthetic Process Lung Alveolus Development Modulation Of Chemical Synaptic Transmission Regulation Of Synapse Organization Leukocyte Migration Regulation Of Protein Transport Response To Redox State Limb Development Lens Fiber Cell Differentiation Platelet Aggregation Glutamate Homeostasis L-glutamate Import Across Plasma Membrane Dipeptide Import Across Plasma Membrane Regulation Of Cysteine Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Glutathione Biosynthetic Process Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Glutamate Metabolic Process
Pathways		Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism	Basigin interactions Amino acid transport across the plasma membrane
Drugs			Cystine Glutamic acid Riluzole Sulfasalazine Acetylcysteine Thimerosal
Diseases
GWAS		Iron status biomarkers (transferrin saturation) ( 28334935)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mood instability ( 31168069) Neurociticism ( 29500382)
Interacting Genes		16 interacting genes: CCR4 EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 MTNR1B NPSR1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL	6 interacting genes: BAAT KRTAP1-1 KRTAP1-3 OTUB1 SLC3A2 TERT
Entrez ID		6520	23657
HPRD ID		01148	09720
Ensembl ID		ENSG00000168003	ENSG00000151012
Uniprot IDs		J3KPF3 P08195	Q9UPY5
PDB IDs		2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V
Enriched GO Terms of Interacting Partners?
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