ARFIP2 and SCAMP1

Data Source:
BioGRID (two hybrid)

		ARFIP2	SCAMP1
Description		ADP ribosylation factor interacting protein 2	secretory carrier membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane	Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Synaptic Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Zymogen Granule Membrane Recycling Endosome Membrane
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Post-Golgi Vesicle-mediated Transport Protein Transport Neutrophil Degranulation
Pathways		Retrograde transport at the Trans-Golgi-Network	Neutrophil degranulation
Drugs
Diseases
GWAS		Malaria ( 31844061)	Hippocampal atrophy ( 19668339) Intraocular pressure ( 29785010) Platelet count ( 32888494) Plateletcrit ( 32888494) Triglycerides ( 26780889)
Interacting Genes		61 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARFIP1 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1	26 interacting genes: ARFIP1 ARFIP2 DNAJC5 EGFR EPS15 GAD2 ITSN1 KRTAP13-1 MTERF3 NDRG4 PBX3 PCYT1A PTPN9 SCAMP2 SLC9A7 SNAP23 SNAP25 SPG21 SYNRG TASOR2 TBRG4 THAP4 TP53 TTPA UBE3A ZMIZ2
Entrez ID		23647	9522
HPRD ID		07209	06072
Ensembl ID		ENSG00000132254	ENSG00000085365
Uniprot IDs		A0A087X1E4 B4DUZ3 B4DXH2 P53365	A0A087WXB0 B4E2V7 O15126
PDB IDs		1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?
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