FBXO25 and LMCD1

Data Source:
BioGRID (enzymatic study)

		FBXO25	LMCD1
Description		F-box protein 25	LIM and cysteine rich domains 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity	Transcription Corepressor Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cardiac Muscle Hypertrophy Cellular Protein Metabolic Process Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways			Surfactant metabolism
Drugs
Diseases
GWAS		Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Brain volume in infants (intracranial brain volume) ( 28763065) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Low high density lipoprotein cholesterol levels ( 26879886) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Platelet count ( 32888494) Plateletcrit ( 32888494) Rumination (response to stress) ( 30886212) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		82 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	9 interacting genes: APP FBXO25 IKBKG NKX3-1 PRKAG3 RABIF TEKT4 TRIM55 TRIM63
Entrez ID		26260	29995
HPRD ID		16439	06891
Ensembl ID		ENSG00000147364	ENSG00000071282
Uniprot IDs		A0A024QZ88 Q8TCJ0	B4DEY6 B7Z6R5 H7C3D2 Q9NZU5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?