FBXO25 and DDX42

Data Source:
BioGRID (enzymatic study)

		FBXO25	DDX42
Description		F-box protein 25	DEAD-box helicase 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Membrane Nuclear Speck
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity	RNA Binding RNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Protein Ubiquitination	MRNA Splicing, Via Spliceosome Protein Localization Regulation Of Apoptotic Process
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Body mass index ( 25673413) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 25673412)
Interacting Genes		82 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	10 interacting genes: APP DHX15 FBXO25 MDM2 PRPF19 RECQL5 SF3A1 SF3B4 SNRPC U2SURP
Entrez ID		26260	11325
HPRD ID		16439	09909
Ensembl ID		ENSG00000147364	ENSG00000198231
Uniprot IDs		A0A024QZ88 Q8TCJ0	Q86XP3
PDB IDs
Enriched GO Terms of Interacting Partners?
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