DECR2 and USP11

Data Source:
BioGRID (two hybrid)

		DECR2	USP11
Description		2,4-dienoyl-CoA reductase 2	ubiquitin specific peptidase 11
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GO Annotations	Cellular Component	Peroxisomal Membrane Cytosol	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity	RNA Polymerase II Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Protein Targeting To Peroxisome Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Deubiquitination Protein Phosphopantetheinylation
Pathways		Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases
Drugs
Diseases
GWAS		Body mass index ( 26426971) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		11 interacting genes: APP C14orf119 EP300 NEDD4L OSGIN1 PEX5 TRIM55 TRIM63 UBC USP11 VPS26C	21 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC
Entrez ID		26063	8237
HPRD ID		16789	02081
Ensembl ID		ENSG00000242612	ENSG00000102226
Uniprot IDs		Q9NUI1	B4DGK3 P51784
PDB IDs		4FC6 4FC7	4MEL 5OK6
Enriched GO Terms of Interacting Partners?
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