GAB1 and NCK2

GAB1

NCK2

Description GRB2 associated binding protein 1 NCK adaptor protein 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 21804548)
  • Diastolic blood pressure ( 27841878)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Height ( 31562340)
  • Malaria ( 31844061)
  • Systolic blood pressure ( 27841878)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 73 interacting genes: ARHGAP32 BCAR3 BLK BLNK BTK C1QBP CRK CRKL EGFR EPOR ERBB2 FCGR2B FES FRS2 GAB2 GRAP2 GRB2 GTF2A1L HCK HSH2D INPP5D INPPL1 INSR ITK JAK1 LAT2 LCK LYN MAP3K3 MAPK1 MAPK3 MAPK4 MARK2 MET MST1R NCK1 NCK2 PDGFRB PIK3CG PIK3R1 PIK3R2 PIK3R3 PLCG1 PLCG2 PTK6 PTPN11 PTPN18 RASA1 RET SH2D1B SH2D2A SH2D3A SHC1 SHC3 SLA SLA2 SOCS3 SOCS6 SOS1 SRC STAP1 SUPT6H SYK SYP TEC TNS1 TNS3 TNS4 TRIM15 VAV1 VAV2 VAV3 YES1 171 interacting genes: ABI1 ABI2 ABI3 ANKRD55 ANKS1B ARHGAP32 ATN1 AXIN1 AXL BCAR1 BCL11A BTG1 C4orf17 CBARP CBLB CCDC120 CCDC33 CD3E CHN1 CHN2 CIB1 CIPC CLEC17A CPSF6 CPSF7 CUEDC1 DDR1 DEFB124 DISC1 DLGAP4 DNM1 DOCK1 DOK1 DRAP1 DTX3 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EFS EGFR EIF3H ERBB2 ERBB3 ERBB4 FAM124A FAM47A FAM53C FAM83A FASLG FBXL19 FCRL2 FGFR1 FOSB FXR2 FYB1 GAB1 GAREM1 GGN HNRNPK HOMEZ HOXA1 HOXC4 HOXD8 HSF2BP ILK INCA1 INTS2 IRS1 KCTD17 KHDRBS1 KIAA0408 KIAA1217 KIT KLHL24 KLHL35 KPRP LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MBD6 MEOX2 MET MIA3 MNT MYPOP NCKIPSD NELFA NET1 NFKBID NHSL2 NPAS2 NPHS1 NR5A1 NTRK2 NUTM2F ONECUT3 PAK1 PAK2 PBX4 PDGFRB PHETA1 PIK3AP1 PKD1 PKN2 PRDM6 PRR16 PRR20A PRR20B PRR20C PRR20D PRR20E PSMD10 PTK2 RASSF7 RBBP8NL RBM26 REEP4 REL SCML2 SCX SF1 SF3A2 SF3B4 SHD SKAP2 SMARCB1 SNW1 SOCS7 SORBS2 SOS1 SPATA2L SPATC1L SPRY2 SRMS SRPK1 SRPK2 SSH3 SYNGAP1 SYNPO TCF4 TCP10L TMEM121 TNR TRIM27 TRIM41 TRIP6 TXK UBC USP32 VARS2 VPS37B WAS WASF1 WASL WBP11 WIPF1 WIPF2 ZBTB12 ZBTB42 ZBTB7B ZC2HC1A ZC2HC1B ZNF341 ZNF526 ZNF688
Entrez ID 2549 8440
HPRD ID 05116 05378
Ensembl ID ENSG00000109458 ENSG00000071051
Uniprot IDs Q13480 Q9HA84 A0A0S2Z4M6 E7ERP6 O43639
PDB IDs 4QSY 1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R
Enriched GO Terms of Interacting Partners?
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